دانلود مقاله Toxin structure and design of therapeutics

دانلود مقاله Toxin structure and design of therapeutics

The A-B Class of Toxins
• A (active) subunit: toxic enzymatic activity
• B (binding) subunit: binding to cell surface
• Examples:
• pertussis toxin (A1; B is heteropentamer)
• Shiga toxin family (A1B5)
• cholera toxin family (A1B5)
• diphtheria toxin (A1B1)
• ricin (A1B1)

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